Putting up your dukes and agreeing to fight has no place in a self-defense repertoire.
I once agreed to "step outside" with a very persistent intoxicated a@s who was interfering with my date.
Told him I would meet him out in the parking lot. Paid the bouncer a substantial tip not to let him back in

Eventually we left the bar in a group and I was in full "condition red". Cost me about the price of the shirt I would had to replace by "stepping out"...or worse.
Thankfully that night my intelligence managed to somehow slip past my emotions.
Learn from nature. No healthy animal will choose to engage in a violent conflict unless there is no other option and the reason for engagement is survival of the pack or themselves.
Why is it that humans voluntarily engage in violent acts with very few of the situations being for reasons of survival? My guess is that our emotions are not in communication with our intelligence.
We do not teach our children about violence, zero tolerance in schools isolates them from what I think is a natural learning process (puppies not learning the boundaries of play-fighting). However, video games train them to be in control of creating very real simulations of violent acts.Acts of violence they control with no real purpose of engagement. What a "dumb species" we can be.
Léo